Fibrinogen beta Antibody

BT-AP03237

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human Fibrinogen β.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The fibrinogen beta chain encoded by FGB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Human: P02675; Mouse: Q8K0E8;

55,928

Human: 2244

FGB; Fibrinogen beta chain

Cardiovascular

FGB