GPT2 Antibody

BT-AP03784

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from GPT2 . at AA range: 190-270

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

GPT2 (glutamic--pyruvic transaminase 2) encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in GPT2 has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.

Human: Q8TD30; Mouse: Q8BGT5;

57904

Human: 84706

GPT2; AAT2; ALT2; Alanine aminotransferase 2; ALT2; Glutamate pyruvate transaminase 2; GPT 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2

Signal Transduction; Metabolism

GPT2