HAT1 Antibody

BT-AP03892

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human HAT. AA range:331-380

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The protein encoded by HAT1 (histone acetyltransferase 1)is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for HAT1.

Human: O14929; Mouse: Q8BY71; Rat: Q5M939;

49513

Human: 8520; Mouse: 107435; Rat: 296501

HAT1; KAT1; Histone acetyltransferase type B catalytic subunit; Histone acetyltransferase 1

Epigenetics and Nuclear Signaling

HAT1