HC-II Antibody

BT-AP03913

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II. AA range:41-90

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

SERPIND1 belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. SERPIND1 encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.

Human: P05546; Mouse: P49182; Rat: Q64268;

57071

Human: 3053; Mouse: 15160; Rat: 79224

SERPIND1; HCF2; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1

Cardiovascular

SERPIND1