Histone deacetylase 1 Polyclonal Antibody

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Home > Product > Antibody > Histone deacetylase 1 Polyclonal Antibody

Histone deacetylase 1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Histone deacetylase 1 Antibody

Code

BT-AP03984

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC1. AA range:433-482

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Uniprot accession

Human: Q13547; Mouse: O09106; Rat: Q4QQW4;

Molecular weight

55103

Gene ID

Human: 3065; Mouse: 433759; Rat: 297893

Synonyms

HDAC1; RPD3L1; Histone deacetylase 1; HD1

Research area

Epigenetics and Nuclear Signaling

Target protein

HDAC1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
IF	1: 200 - 1: 1000
ELISA	1: 10000

Images

Western Blot analysis of hela cells using Histone deacetylase 1 Polyclonal Antibody diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Western Blot analysis of various cells using Histone deacetylase 1 Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from NIH/3T3 cells, using HDAC1 Antibody. The lane on the right is blocked with the synthesized peptide.

Immunofluorescence analysis of NIH/3T3 cells, using HDAC1 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HDAC1 Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

References

Customer reviews and Q&As

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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