Histone deacetylase 6 Antibody

BT-AP03986

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human HDAC6. AA range:1166-1215

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Human: Q9UBN7; Mouse: Q9Z2V5;

131431

Human: 10013; Mouse: 15185

HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

Epigenetics and Nuclear Signaling

HDAC6