HNF-4alpha/gamma Antibody

BT-AP04159

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human HNF-4α/γ around the non-acetylation site of K127.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Hepatocyte nuclear factor 4-alpha/Hepatocyte nuclear factor 4-gamma encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Human: P41235; Mouse: P49698; Rat: P22449;

52785

Human: 3172; Mouse: 15378; Rat: 25735

HNF4A; HNF4; NR2A1; TCF14; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14;Transcription factor HNF-4; HNF4G; NR2A2; Hepa

Cardiovascular

HNF4A