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Background
The protein encoded by IL17RB (interleukin 17 receptor B) is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of IL17RB was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
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Recommended dilution
| Application | Dilution |
|---|---|
| WB | 1: 500 - 2000 |
| ELISA | 1: 10000 - 20000 |
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