KLF12 Antibody

BT-AP04837

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human KLF12.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Krueppel-like factor 12 encoded by KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Human: Q9Y4X4; Mouse: O35738;

44240

Human: 11278; Mouse: 16597

KLF12; AP2REP; HSPC122; Krueppel-like factor 12; Transcriptional repressor AP-2rep

Epigenetics and Nuclear Signaling

KLF12