MLH1 Antibody

BT-AP05452

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Human: P40692; Mouse: Q9JK91; Rat: P97679;

84601

Human: 4292; Mouse: 17350; Rat: 81685

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Epigenetics and Nuclear Signaling

MLH1