Myosin VI Antibody

BT-AP05732

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from Myosin VI . at AA range: 40-120

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

MYO6 encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The unconventional myosin-VI consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Human: Q9UM54; Mouse: Q64331;

149691

Human: 4646

MYO6; KIAA0389; Unconventional myosin-VI; Unconventional myosin-6

Signal Transduction

MYO6