OMG Antibody

BT-AP06569

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human OMG. AA range:282-331

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells; from dorsal root ganglion explants in which growth cone collapse was observed; from rat retinal ganglion neurons; and from NG108 and PC-12 cells.

Human: P23515; Mouse: Q63912;

49608

Human: 4974

OMG; OMGP; Oligodendrocyte-myelin glycoprotein

Neuroscience

OMG