PI 3-Kinase C2gamma Antibody

BT-AP07134

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The protein encoded by PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma) belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. PIK3C2G may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants.

Human: O75747; Mouse: O70167;

166095

Human: 5288

PIK3C2G; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma

Others

PIK3C2G