PTPalpha Antibody

BT-AP07504

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from PTPα . at AA range: 730-810

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The protein encoded by PTPRA (protein tyrosine phosphatase, receptor type A) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of PTPRA, which encode two distinct isoforms, have been reported.

Human: P18433; Mouse: P18052; Rat: Q03348;

90600

Human: 5786; Mouse: 19262

PTPRA; PTPA; PTPRL2; Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha; R-PTP-alpha

Signal Transduction

PTPRA