RNase III Drosha Polyclonal Antibody

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Home > Product > Antibody > RNase III Drosha Polyclonal Antibody

RNase III Drosha Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, ELISA

Product overview

Full product name

RNase III Drosha Antibody

Code

BT-AP07946

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human RNase III Drosha. AA range:774-823

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al. 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al. 2003 [PubMed 14508493]).

Uniprot accession

Human: Q9NRR4; Mouse: Q5HZJ0;

Molecular weight

159316

Gene ID

Human: 29102; Mouse: 14000

Synonyms

DROSHA; RN3; RNASE3L; RNASEN; Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241

Research area

Epigenetics and Nuclear Signaling

Target protein

DROSHA

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 10000

Images

Western blot analysis of lysates from brain tissue, using RNase III Drosha antibody.

Western blot analysis of SH-SY5Y K562 HELA using RNase III Drosha antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000 cells nucleus.

Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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