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Home > Product > Antibody > SR-2B Polyclonal Antibody

SR-2B Polyclonal Antibody

SR-2B Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IF, ELISA

Product overview

Full product name

SR-2B Antibody

Code

BT-AP08535

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human HTR2B. AA range:15-64

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

HTR2B encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.

Uniprot accession

Molecular weight

54298

Gene ID

Human: 3357

Synonyms

HTR2B; 5-hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; Serotonin receptor 2B

Research area

Neuroscience

Target protein

HTR2B

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IF 1: 200 - 1: 1000
ELISA 1: 10000

Images

Western Blot analysis of various cells using SR-2B Polyclonal Antibody
Western blot analysis of the lysates from COLO205 cells using HTR2B antibody.
Immunofluorescence analysis of COS7 cells, using HTR2B Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HT-29, 293, and HeLa cells, using HTR2B Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

Add to Cart

Lead time: Within one week

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