STK36 Antibody

BT-AP08659

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human STK36. AA range:387-436

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

STK36 encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that STK36 is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.

Human: Q9NRP7; Mouse: Q69ZM6;

143995

Human: 27148; Mouse: 269209

STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog

Signal Transduction

STK36