TCP-1 alpha Antibody

BT-AP08898

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human TCP-1 α.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The protein encoded by TCP1 (t-complex 1) is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of TCP1, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from TCP1 have been found.

Human: P17987; Mouse: P11983; Rat: P28480;

60344

Human: 6950; Mouse: 21454; Rat: 24818

TCP1; CCT1; CCTA; T-complex protein 1 subunit alpha; TCP-1-alpha; CCT-alpha

Signal Transduction

TCP1