Topo IIIalpha Antibody

BT-AP09128

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from Topo IIIα . at AA range: 350-430

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

TOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Human: Q13472; Mouse: O70157;

112372

Human: 7156; Mouse: 21975

TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

Epigenetics and Nuclear Signaling

TOP3A