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Home > Product > Antibody > uPA Polyclonal Antibody

uPA Polyclonal Antibody

uPA Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: IHC-p, ELISA

Product overview

Full product name

uPA Antibody

Code

BT-AP09424

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human uPA. AA range:190-239

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

PLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in PLAU may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Uniprot accession

Molecular weight

48525

Gene ID

Human: 5328

Synonyms

PLAU; Urokinase-type plasminogen activator; U-plasminogen activator; uPA

Research area

Neuroscience

Target protein

PLAU

Recommended dilution

Application Dilution
IHC 1: 100 - 1: 300
ELISA 1: 40000

Images

Immunohistochemistry analysis of uPA antibody in paraffin-embedded human brain tissue.

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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