VRK3 Antibody

BT-AP09557

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human VRK3.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.

Human: Q8IV63; Mouse: Q8K3G5;

52881

Human: 51231

VRK3; Inactive serine/threonine-protein kinase VRK3; Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3

Signal Transduction

VRK3