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Home > Product > Antibody > Wnt-1 Polyclonal Antibody

Wnt-1 Polyclonal Antibody

Wnt-1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Wnt-1 Antibody

Code

BT-AP09593

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human WNT1. AA range:301-350

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. Proto-oncogene Wnt-1 have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT1 is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Uniprot accession

Molecular weight

40982

Gene ID

Human: 7471; Mouse: 22408

Synonyms

WNT1; INT1; Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog

Research area

Stem Cells

Target protein

WNT1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC 1: 100 - 1: 300
IF 1: 200 - 1: 1000
ELISA 1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using WNT1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot analysis of HT29 cells using Wnt-1 Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000
Western Blot analysis of various cells using Wnt-1 Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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