XRCC1 Antibody

BT-AP09623

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

DNA repair protein XRCC1 encoded by XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Human: P18887; Mouse: Q60596; Rat: Q9ESZ0;

69526

Human: 7515; Mouse: 22594; Rat: 84495

XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1

Epigenetics and Nuclear Signaling

XRCC1