Phospho-Btk (Y223) Polyclonal Antibody

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Home > Product > Antibody > Phospho-Btk (Y223) Polyclonal Antibody

Phospho-Btk (Y223) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, mouse, rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, mouse, rat

Applications: WB, ELISA

Product overview

Full product name

Phospho-Btk (Y223) Antibody

Code

BT-PHS00287

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human BTK around the phosphorylation site of Tyr223. AA range:188-237

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Bruton tyrosine kinase encoded by BTK plays a crucial role in B-cell development. Mutations in BTK cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Uniprot accession

Human: Q06187; Mouse: P35991;

Molecular weight

76150

Gene ID

Human: 695; Mouse: 12229

Synonyms

BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase

Research area

Signal Transduction

Target protein

BTK

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 40000

Protocols

> Protocol Booklet

References

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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