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Home > Product > ELISA Kit > Human Atp-sensitive Inward Rectifier Potassium Channel 11, KCNJ11 ELISA Kit

Human Atp-sensitive Inward Rectifier Potassium Channel 11, KCNJ11 ELISA Kit

Human Atp-sensitive Inward Rectifier Potassium Channel 11, KCNJ11 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 8.87ng/L

Detection range: 20-6000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 8.87ng/L

Detection range: 20-6000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

ATP-sensitive inward rectifier potassium Channel 11

Code

E1796Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

8.87ng/L

Detection range

20-6000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

UniProt accession

MASS(Da)

43,541

GeneID

3767

Synonyms

ATP-sensitive inward rectifier potassium Channel 11;BIR;HHF2;IKATP;Inward rectifier K(+ Channel Kir6.2;KCNJ11;MODY13;PHHI;PNDM2;Potassium Channel, inwardly rectifying subfamily J member 11;TNDM3

Gene names

KCNJ11

Research area

Neuroscience

Target protein

KCNJ11

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1796Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
3200ng/L 2.357 2.352 2.278
2.346
1600ng/L 1.275 1.327 1.253
1.379
800ng/L 0.907 0.882 0.808
0.858
400ng/L 0.478 0.459 0.385
0.441
200ng/L 0.311 0.29 0.216
0.268
0ng/L 0.07 0.074 0
0.078

Precision

We measured random samples of E1796Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 794.44 45.31 5.7
Intra-Assay 2 18 1814.4 54.41 3
Intra-Assay 3 18 714.47 47.41 6.64

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E1796Hu

    $320.00

  • 96T

    E1796Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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