L-lactate dehydrogenase B chain

E2215Mo

Sandwich

48T,96T

0.25mU/mL

0.5-300mU/mL

Serum, plasma, cell culture supernates

Mouse

2-8ºC

1h 30m

Lactate dehydrogenase B is a protein that in humans is encoded by the LDHB gene. This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

36,572

16832

AI790582;H-Ld;H-Ldh;Ldh-;LDH heart subunit;Ldh2;LDHB;LDH-B;LDH-H;L-lactate dehydrogenase B chain

Ldhb

Others

LDHB