Carbohydrate Sulfotransferase 15

E2872Hu

Sandwich

48T,96T

0.043ng/ml

0.1-40ng/ml

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO4) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

64,926

51363

B-cell RAG-associated gene protein;BRAG;Carbohydrate sulfotransferase 15;CHST15;GALNAC4S-6ST;hBRAG;N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

CHST15

Immunology

CHST15