Human Cubilin, CUBN ELISA Kit

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Home > Product > ELISA Kit > Human Cubilin, CUBN ELISA Kit

Human Cubilin, CUBN ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.28ng/ml

Detection range: 0.5-150ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.28ng/ml

Detection range: 0.5-150ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Cubilin

Code

E3631Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.28ng/ml

Detection range

0.5-150ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake (PubMed: 9572993, PubMed: 10371504, PubMed: 11717447, PubMed: 11606717, PubMed: 14576052). Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex (PubMed: 9572993, PubMed: 14576052). Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium (PubMed: 9572993). Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.

UniProt accession

O60494

MASS（Da）

398,736

GeneID

8029

Synonyms

460 kDa receptor;Cubilin;CUBN;Intestinal intrinsic factor receptor;Intrinsic factor-cobalamin receptor;Intrinsic factor-vitamin B12 receptor

Gene names

CUBN

Research area

Signal Transduction

Target protein

CUBN

Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Protocol data

These standard curves of E3631Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
80ng/ml	2.11	2.08	2.051
	2.05
40ng/ml	1.737	1.638	1.609
	1.538
20ng/ml	1.024	0.991	0.963
	0.958
10ng/ml	0.629	0.646	0.617
	0.663
5ng/ml	0.474	0.446	0.417
	0.418
0ng/ml	0.03	0.028	0
	0.027

Precision

We measured random samples of E3631Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	46.4	2.85	6.1
Intra-Assay	2	18	11	0.84	7.6
Intra-Assay	3	18	14.2	0.86	6.1

Protocols

> Protocol Booklet

References

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Associated products

Datasheet

Size

Code

Price

48T

E3631Hu

$320.00
96T

E3631Hu

$458.00

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Lead time: Within two weeks

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