Elongation of very long chain fatty acids protein 2

E5233Hu

Sandwich

48T,96T

1.49ng/L

3-900ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

34,585

54898

3-keto acyl-CoA Synthase ELOVL2;Elongation of very long chain fatty acids protein 2;ELOVL FA elongase 2;ELOVL fatty acid elongase 2;ELOVL2;SSC2;Very long chain 3-ketoacyl-CoA Synthase 2;Very long chain 3-oxoacyl-CoA Synthase 2

ELOVL2

Cardiovascular

ELOVL2