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Home > Product > ELISA Kit > Human SIgMa Non-opioid Intracellular Receptor 1, SIgMAR1 ELISA Kit

Human SIgMa Non-opioid Intracellular Receptor 1, SIgMAR1 ELISA Kit

Human SIgMa Non-opioid Intracellular Receptor 1, SIgMAR1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.026ng/mL

Detection range: 0.05-20ng/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.026ng/mL

Detection range: 0.05-20ng/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Sigma non-opioid intracellular receptor 1

Code

E6175Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.026ng/mL

Detection range

0.05-20ng/mL

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (PubMed:16472803, PubMed:9341151). Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria. Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112 (By similarity).

UniProt accession

MASS(Da)

25,128

GeneID

10280

Synonyms

Aging-associated gene 8 protein;ALS16;DSMA2;hSigmaR1;OPRS1;SIG-1R;Sigma 1-type opioid receptor;Sigma non-opioid intracellular receptor 1;sigma1R;Sigma1-receptor;SIGMAR1;SR31747-binding protein;SRBP;SR-BP

Gene names

SIGMAR1

Research area

Others

Target protein

SIGMAR1

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E6175Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
12ng/mL 2.197 2.237 2.18
2.278
6ng/mL 1.463 1.377 1.321
1.292
3ng/mL 0.902 0.926 0.869
0.949
1.5ng/mL 0.497 0.47 0.413
0.443
0.75ng/mL 0.298 0.274 0.217
0.25
0ng/mL 0.064 0.057 0
0.05

Precision

We measured random samples of E6175Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 1.14 0.05 4.68
Intra-Assay 2 18 3.86 0.17 4.32
Intra-Assay 3 18 7.58 0.3 3.98

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E6175Hu

    $320.00

  • 96T

    E6175Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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