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Home > Product > ELISA Kit > Human Nkg2-D Type 2 Integral Membrane Protein, KLRK1 ELISA Kit

Human Nkg2-D Type 2 Integral Membrane Protein, KLRK1 ELISA Kit

Human Nkg2-D Type 2 Integral Membrane Protein, KLRK1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.054ng/ml

Detection range: 0.1-40ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.054ng/ml

Detection range: 0.1-40ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Nkg2-D Type 2 Integral Membrane Protein

Code

E4183hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.054ng/ml

Detection range

0.1-40ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, RAET1L/ULBP6, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.

UniProt accession

MASS(Da)

25,274

GeneID

10052803222914

Synonyms

CD antigen CD314;Killer cell lectin-like receptor subfamily K member 1;KLRK 1;KLRK1;NK cell receptor D;NKG2-D type II integral membrane protein;NKG2-D-activating NK receptor

Gene names

KLRK1

Research area

Others

Target protein

KLRK1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E4183hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
24ng/ml 2.333 2.345 2.298
2.357
12ng/ml 1.545 1.528 1.481
1.511
6ng/ml 1.196 1.183 1.136
1.17
3ng/ml 0.641 0.661 0.613
0.68
1.5ng/ml 0.412 0.406 0.359
0.4
0ng/ml 0.04 0.047 0
0.054

Precision

We measured random samples of E4183hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%

Protocols

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E4183hu

    $320.00

  • 96T

    E4183hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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