Human Inhibitor of Growth Protein 4, ING4 ELISA Kit

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Blood coagulation
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Home > Product > ELISA Kit > Human Inhibitor of Growth Protein 4, ING4 ELISA Kit

Human Inhibitor of Growth Protein 4, ING4 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 9.82ng/L

Detection range: 20-6000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 9.82ng/L

Detection range: 20-6000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Inhibitor of Growth Protein 4

Code

E5465Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

9.82ng/L

Detection range

20-6000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed: 16387653). Through chromatin acetylation it may function in DNA replication (PubMed: 16387653). May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed: 15251430, PubMed: 15528276). Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA (PubMed: 15029197). May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC (PubMed: 15029197). Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (PubMed: 15897452). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).

UniProt accession

Q9UNL4

MASS（Da）

28,530

GeneID

51147

Synonyms

ING 4;ING4;Inhibitor of growth protein 4;p29ING4

Gene names

ING4

Research area

Cancer

Target protein

ING4

Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Protocol data

These standard curves of E5465Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
3200ng/L	2.15	2.188	2.158
	2.226
1600ng/L	1.557	1.591	1.561
	1.624
800ng/L	1.191	1.141	1.111
	1.09
400ng/L	0.735	0.732	0.702
	0.729
200ng/L	0.45	0.439	0.409
	0.427
0ng/L	0.027	0.03	0
	0.032

Precision

We measured random samples of E5465Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%

Protocols

> Protocol Booklet

References

Customer reviews and Q&As

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Associated products

Datasheet

Size

Code

Price

48T

E5465Hu

$320.00
96T

E5465Hu

$458.00

Add to Cart

Lead time: Within two weeks

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