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Home > Product > ELISA Kit > Human Multidrug Resistance-associated Protein 1, ABCC1 ELISA Kit

Human Multidrug Resistance-associated Protein 1, ABCC1 ELISA Kit

Human Multidrug Resistance-associated Protein 1, ABCC1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 4.34ng/mL

Detection range: 10-2000ng/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 4.34ng/mL

Detection range: 10-2000ng/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Multidrug Resistance-Associated Protein 1

Code

E5702Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

4.34ng/mL

Detection range

10-2000ng/mL

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Mediates export of organic anions and drugs from the cytoplasm (PubMed: 7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed: 7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed: 9281595). Hydrolyzes ATP with low efficiency (PubMed: 16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed: 17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).

UniProt accession

MASS(Da)

171,591

GeneID

4363

Synonyms

ABCC 1;ABCC1;ATP-binding cassette sub-family C member 1;Glutathione-S-conjugate-translocating ATPase ABCC1;Leukotriene C(4 transporter;LTC4 transporter;Multidrug resistance-associated protein 1

Gene names

ABCC1

Research area

Others

Target protein

ABCC1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E5702Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1200ng/mL 2.001 2.063 2.02
2.125
600ng/mL 1.061 0.988 0.944
0.914
300ng/mL 0.569 0.51 0.466
0.45
150ng/mL 0.167 0.236 0.192
0.305
75ng/mL 0.126 0.14 0.096
0.153
0ng/mL 0.036 0.043 0
0.05

Precision

We measured random samples of E5702Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 667.7 31.03 4.6
Intra-Assay 2 18 850.8 20.47 2.4
Intra-Assay 3 18 283.3 14.73 5.2

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E5702Hu

    $320.00

  • 96T

    E5702Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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