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Home > Product > ELISA Kit > Human Natural Cytotoxicity Triggering Receptor 3, NCR3 ELISA Kit

Human Natural Cytotoxicity Triggering Receptor 3, NCR3 ELISA Kit

Human Natural Cytotoxicity Triggering Receptor 3, NCR3 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 4.47ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 4.47ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Natural Cytotoxicity Triggering Receptor 3

Code

E5741Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

4.47ng/L

Detection range

10-2000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

UniProt accession

MASS(Da)

21,593

GeneID

259197

Synonyms

Activating natural killer receptor p30;CD antigen CD337;Natural cytotoxicity triggering receptor 3;Natural killer cell p30-related protein;NCR 3;NCR3;NKp30;NK-p30

Gene names

NCR3

Research area

Others

Target protein

NCR3

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E5741Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1200ng/L 1.905 1.898 1.843
1.892
600ng/L 0.984 1.022 0.967
1.06
300ng/L 0.521 0.473 0.418
0.425
150ng/L 0.158 0.205 0.15
0.251
75ng/L 0.123 0.103 0.049
0.083
0ng/L 0.056 0.055 0
0.053

Precision

We measured random samples of E5741Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 863 25.62 3
Intra-Assay 2 18 424.1 20.5 4.8
Intra-Assay 3 18 476.2 16.48 3.5

Protocols

References

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E5741Hu

    $320.00

  • 96T

    E5741Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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