C-C Motif Chemokine 2

E0170HO

Sandwich

96T,48T

2.68ng/L

5-1000ng/L

Serum, plasma, cell culture supernates

Horse

2-8ºC

1h 30m

Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).

10,790

100034136

C-C motif chemokine 2;CCL 2;CCL2;MCP-1;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;Small-inducible cytokine A2

CCL2

Others

CCL2