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Home > Product > ELISA Kit > Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit

Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit

Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.31ng/ml

Detection range: 0.5-150ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.31ng/ml

Detection range: 0.5-150ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

C-X-C Chemokine Receptor Type 3

Code

E7269Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.31ng/ml

Detection range

0.5-150ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

[Isoform 1]: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed: 12782716). Binds to CCL21. Probably promotes cell chemotaxis response. [Isoform 2]: Receptor for the C-X-C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the proliferation, survival and angiogenic activity of human microvascular endothelial cells (HMVEC) through a cAMP-mediated signaling pathway (PubMed: 12782716). Does not promote cell chemotaxis respons. Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis. [Isoform 3]: Mediates the activity of CXCL11.

UniProt accession

MASS(Da)

40,660

GeneID

2833

Synonyms

CD antigen CD183;CKR-L2;C-X-C chemokine receptor type 3;CXCR 3;CXCR3;CXCR-3;CXC-R3;G protein-coupled receptor 9;Interferon-inducible protein 10 receptor;IP-10 receptor

Gene names

CXCR3

Research area

Immunology

Target protein

CXCR3

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E7269Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected

Precision

We measured random samples of E7269Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 33.4 0.98 2.95
Intra-Assay 2 18 24.01 1.17 4.89
Intra-Assay 3 18 10.84 0.57 5.23

Protocols

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E7269Hu

    $320.00

  • 96T

    E7269Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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