Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit

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Home > Product > ELISA Kit > Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit

Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.31ng/ml

Detection range: 0.5-150ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.31ng/ml

Detection range: 0.5-150ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

C-X-C Chemokine Receptor Type 3

Code

E7269Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.31ng/ml

Detection range

0.5-150ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

[Isoform 1]: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed: 12782716). Binds to CCL21. Probably promotes cell chemotaxis response. [Isoform 2]: Receptor for the C-X-C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the proliferation, survival and angiogenic activity of human microvascular endothelial cells (HMVEC) through a cAMP-mediated signaling pathway (PubMed: 12782716). Does not promote cell chemotaxis respons. Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis. [Isoform 3]: Mediates the activity of CXCL11.

UniProt accession

P49682

MASS（Da）

40,660

GeneID

2833

Synonyms

CD antigen CD183;CKR-L2;C-X-C chemokine receptor type 3;CXCR 3;CXCR3;CXCR-3;CXC-R3;G protein-coupled receptor 9;Interferon-inducible protein 10 receptor;IP-10 receptor

Gene names

CXCR3

Research area

Immunology

Target protein

CXCR3

Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Protocol data

These standard curves of E7269Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected

Precision

We measured random samples of E7269Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	33.4	0.98	2.95
Intra-Assay	2	18	24.01	1.17	4.89
Intra-Assay	3	18	10.84	0.57	5.23

Protocols

> Protocol Booklet

References

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Associated products

Datasheet

Size

Code

Price

48T

E7269Hu

$320.00
96T

E7269Hu

$458.00

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Lead time: Within two weeks

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