Intelectin-1

E0155Hu

Sandwich

96T,48T

1.03ng/L

2-600ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed: 11313366, PubMed: 26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed: 26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed: 26148048). Does not bind human glycans (PubMed: 26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed: 16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed: 16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed: 11747454, PubMed: 23921499).

34,962

55600

Endothelial lectin HL-1;Galactofuranose-binding lectin;Intelectin-1;Intestinal lactoferrin receptor;ITLN 1;ITLN1;ITLN-1;Omentin

ITLN1

Cardiovascular

ITLN1