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Home > Product > ELISA Kit > Human Membrane Co Factor Protein, MCP ELISA Kit

Human Membrane Co Factor Protein, MCP ELISA Kit

Human Membrane Co Factor Protein, MCP ELISA Kit

Product Summary

Size: 96T,48T

Sensitivity: 0.51ng/ml

Detection range: 1-400ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 96T,48T

Sensitivity: 0.51ng/ml

Detection range: 1-400ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Membrane Cofactor Protein

Code

E0275Hu

Assay type

Sandwich

Size

96T,48T

Sensitivity

0.51ng/ml

Detection range

1-400ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. (Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells. (Microbial infection) Acts as a receptor for Adenovirus subgroup B2 and Ad3. (Microbial infection) Acts as a receptor for cultured Measles virus. (Microbial infection) Acts as a receptor for Herpesvirus 6/HHV-6. (Microbial infection) May act as a receptor for pathogenic bacteria Neisseria and Streptococcus pyogenes (PubMed: 7708671, PubMed: 9379894, PubMed: 11260136, PubMed: 11971006).

UniProt accession

MASS(Da)

43,747

GeneID

4179

Synonyms

CD 46;CD antigen CD46;CD46;Membrane cofactor protein;TLX;Trophoblast leukocyte common antigen

Gene names

CD46

Research area

Immunology

Target protein

CD46

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E0275Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
240ng/ml 2.273 2.165 2.121
2.057
120ng/ml 1.694 1.637 1.593
1.58
60ng/ml 0.973 1.016 0.972
1.06
30ng/ml 0.781 0.711 0.667
0.641
15ng/ml 0.49 0.455 0.411
0.42
0ng/ml 0.048 0.044 0
0.04

Precision

We measured random samples of E0275Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%

Protocols

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 96T

    E0275Hu

    $458.00

  • 48T

    E0275Hu

    $320.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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