Alpha-1-antitrypsin

96 Test

15.55ng/ml

30 - 9000ng/ml

Serum, plasma, cell culture supernatant

EA0075Ra

Competitive

Rat

2-8ºC

2h 30m

Alpha-1 antitrypsin or alpha1-antitrypsin (A1AT, alpha1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin).[5] In older biomedical literature it was sometimes called serum trypsin inhibitor (STI, dated terminology), because its capability as a trypsin inhibitor was a salient feature of its early study. As a type of enzyme inhibitor, it protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 0.9–2.3 g/L (in the US the reference range is expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation.

Alpha-1-antiproteinase;Alpha-1-antitrypsin;Alpha-1-proteinase inhibitor;Serpin A1;SERPINA1

Cardiovascular

SERPINA1