Chromogranin-A

E1730Hu

Sandwich

48T,96T

15.21ng/L

30-9000ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

[Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Catestatin]: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist (PubMed: 15326220). Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa (PubMed: 15723172 and PubMed: 24723$458.00|$300.00). Can induce mast cell migration, degranulation and production of cytokines and chemokines (PubMed: 21214543). Acts as a potent scavenger of free radicals in vitro (PubMed: 24723$458.00|$300.00). May play a role in the regulation of cardiac function and blood pressure (PubMed: 18541522). [Serpinin]: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.

50,688

1113

AL-11;Catestatin;CgA;CHGA;Chromogranin-A;EA-92;ER-37;ES-43;GE-25;GR-44;GV-19;LF-19;Pancreastatin;p-Glu serpinin precursor;Pituitary secretory protein I;Serpinin;Serpinin-RRG;SL21;SP-I;SS-18;Vasostatin I;Vasostatin II;Vasostatin-1;Vasostatin-2;WA-8;WE-14

CHGA

Neuroscience

CHGA