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Home > Product > ELISA Kit > Human Interleukin 17C, IL-17C ELISA Kit

Human Interleukin 17C, IL-17C ELISA Kit

Human Interleukin 17C, IL-17C ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 15.49ng/L

Detection range: 30-9000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 15.49ng/L

Detection range: 30-9000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Interleukin 17C

Code

E2160Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

15.49ng/L

Detection range

30-9000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial Peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial Peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.

UniProt accession

MASS(Da)

21,765

GeneID

27189

Synonyms

Cytokine CX2;IL 17C;IL17C;IL-17C;Interleukin-17C

Gene names

IL17C

Research area

Immunology

Target protein

IL17C

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E2160Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
4800ng/L 2.165 2.218 2.187
2.27
2400ng/L 1.261 1.288 1.257
1.314
1200ng/L 0.612 0.639 0.608
0.666
600ng/L 0.419 0.378 0.347
0.336
300ng/L 0.177 0.185 0.154
0.193
0ng/L 0.033 0.031 0
0.028

Precision

We measured random samples of E2160Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 3444.5 82.33 2.4
Intra-Assay 2 18 1617.4 83.45 5.2
Intra-Assay 3 18 882.3 45.54 5.2

Protocols

References

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E2160Hu

    $320.00

  • 96T

    E2160Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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