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Home > Product > ELISA Kit > Bovine C-X-C Motif Chemokine 10, CXCL10 ELISA Kit

Bovine C-X-C Motif Chemokine 10, CXCL10 ELISA Kit

Bovine C-X-C Motif Chemokine 10, CXCL10 ELISA Kit

Product Summary

Size: 96T,48T

Sensitivity: 12.56ng/L

Detection range: 30-9000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Bovine

Product Summary

Size: 96T,48T

Sensitivity: 12.56ng/L

Detection range: 30-9000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Bovine

Product overview

Full product name

C-X-C Motif Chemokine 10

Code

E2202Bo

Assay type

Sandwich

Size

96T,48T

Sensitivity

12.56ng/L

Detection range

30-9000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Bovine

Storage

2-8ºC

Assay time

1h 30m

Background

Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity). Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (By similarity). Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization. In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation (By similarity). Activation of the CXCL10/CXCR3 axis plays also an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization (By similarity).

UniProt accession

MASS(Da)

11,427

GeneID

615107

Synonyms

C-X-C motif chemokine 10;CXCL 10;CXCL10;Small-inducible cytokine B10

Gene names

CXCL10

Research area

Immunology; Microbiology; Cancer

Target protein

CXCL10

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E2202Bo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
4800ng/L 2.445 2.282 2.239
2.12
2400ng/L 1.28 1.291 1.247
1.302
1200ng/L 0.705 0.738 0.694
0.77
600ng/L 0.448 0.482 0.438
0.516
300ng/L 0.3 0.301 0.257
0.302
0ng/L 0.046 0.044 0
0.042

Precision

We measured random samples of E2202Bo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 2036 112.56 5.5
Intra-Assay 2 18 2806.8 94.16 3.4
Intra-Assay 3 18 406.7 23.16 5.7

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 96T

    E2202Bo

    $458.00

  • 48T

    E2202Bo

    $320.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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