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Home > Product > Antibody > CD8 Monoclonal Antibody

CD8 Monoclonal Antibody

CD8 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: FCM, ELISA

Product overview

Full product name

T-cell surface glycoprotein CD8 alpha chain

Code

BT-MCA0317

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human CD8 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified antibody in PBS containing 0.03% sodium azide.

Storage

-20°C for one year

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 925

Synonyms

CD8A; MAL; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8; Leu-2; CD antigen CD8a

Research area

Immunology; Cancer

Target protein

CD8A

Recommended dilution

Application Dilution
ELISA 1:10000
FC 1:200 - 1:400

Images

Flow cytometric analysis of blood T cells using CD8 Monoclonal antibody (M2) and negative control (M1).

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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