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Home > Product > Antibody > LIN-28 Monoclonal Antibody

LIN-28 Monoclonal Antibody

LIN-28 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IF, ICC, ELISA

Product overview

Full product name

Protein lin-28 homolog A

Code

BT-MCA0845

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of LIN-28 (aa93-209) expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Antibody are purified by protein G affinity chromatography. Liquid in 0.01M Phosphate buffer, pH 7.4 containing 0.03% sodium azide.

Storage

-20°C for one year

Background

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 79727

Synonyms

LIN28A; CSDD1; LIN28; ZCCHC1; Protein lin-28 homolog A; Lin-28A; Zinc finger CCHC domain-containing protein 1

Research area

Epigenetics and nuclear signaling; Cancer

Target protein

LIN28A

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using LIN-28 Monoclonal antibody against NTERA-2 cell lysate (1).
Confocal immunofluorescence analysis of NTERA-2 cells using LIN-28 Monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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