DNA-directed RNA polymerase II subunit RPB1

BT-AP07909

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human POLR2A around the phosphorylation site of Ser1619. AA range:1585-1634

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes the largest subunit of RNA polymerase II| the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition| this subunit| in combination with several other polymerase subunits| forms the DNA binding domain of the polymerase| a groove in which the DNA template is transcribed into RNA.

Human: P24928; Mouse: P08775;

217206

Human: 5430; Mouse: 20020

DNA-directed RNA polymerase II subunit RPB1; POLR2A; POLR2; DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1

Epigenetics and nuclear signaling

POLR2A