VEGFR2

BT-AP08279

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthetic peptide from human protein at AA range: 1268-1341

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor| known as kinase insert domain receptor| is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation| survival| migration| tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors| including Rab GTPase| P2Y purine nucleotide receptor| integrin alphaVbeta3| T-cell protein tyrosine phosphatase| etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Human: P35968; Mouse: P35918; Rat: O08775;

Human: 3791; Mouse: 0

VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309)

Cancer; Cardiovascular; Signal transduction; Metabolism; Microbiology; Stem cells; Immunology

KDR