IKK alpha(Phospho Thr23) Polyclonal Antibody

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Home > Product > Antibody > IKK alpha(Phospho Thr23) Polyclonal Antibody

IKK alpha(Phospho Thr23) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Inhibitor of nuclear factor kappa-B kinase subunit alpha

Code

BT-AP08997

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human IKK-alpha around the phosphorylation site of Thr23. AA range:15-64

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein| a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex| phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway| thereby activating the transcription factor.

Uniprot accession

Human: O15111; Mouse: Q60680;

Molecular weight

84654

Gene ID

Human: 1147

Synonyms

Inhibitor of nuclear factor kappa-B kinase subunit alpha; CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B

Research area

Cancer; Cardiovascular; Cell biology; Signal transduction; Immunology

Target protein

CHUK

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 5000

Images

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using IKK-alpha (Phospho-Thr23) Antibody. The picture on the right is blocked with the phospho peptide.

Western Blot analysis of various cells using Phospho-IKKα (T23) Polyclonal Antibody diluted at 1:1000

Western Blot analysis of KB cells using Phospho-IKKα (T23) Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from MDA-MB-435 cells treated with EGF, using IKK-alpha (Phospho-Thr23) Antibody. The lane on the left is blocked with the phospho peptide.

Protocols

> Protocol Booklet

References

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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