Transcription factor NF-E2 45 kDa subunit

BT-AP09118

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis| heme synthesis| and the procurement of iron.|Belongs to the bZIP family.|Belongs to the bZIP family. CNC subfamily.|Contains 1 bZIP domain.|subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis.|tissue specificity:Expressed in hematopoietic cells and also in colon and testis.|

Human: Q16621; Mouse: Q07279; Rat: Q6AYT2;

Human: 4778

Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2;Nuclear factor; erythroid-derived 2 45 kDa subunit;p45 NF-E2)

Epigenetics and nuclear signaling

NFE2