FBW1B

BT-AP02642

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human FBW1B

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and| in addition to an F-box| contains multiple WD40 repeats. This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Human: Q9UKB1; Mouse: Q5SRY7;

59620

Human: 23291; Mouse: 103583

FBW1B

Epigenetics and nuclear signaling; Signal transduction

FBXW11